B-17: Fortress in the Sky is an action-packed simulation game for the Nintendo DS where players take to the skies in the iconic B-17 Flying Fortress bomber during World War II. As a member of the USAAF, the gamer is tasked with piloting and managing different positions in the bomber, including gunner, bombardier, and navigator. Engaging in missions that involve strategic bombing runs over Europe, players must fend off enemy fighters, manage repairs, and ensure the safety of their crew. The game combines elements of aerial combat and strategy, immersing players in historical wartime aviation.