Jimmy Neutron: Attack of the Twonkies for the Game Boy Advance is an action-adventure platformer. In this game, players control the boy genius Jimmy Neutron as he endeavors to save Retroville from the mischievous Twonkies. These creatures mutate into monsters when exposed to music. Players must use Jimmy's inventive gadgets, solve puzzles, and overcome various challenges while exploring different environments inspired by the popular TV series. The game combines elements of exploration, problem-solving, and combat, appealing to fans of the show and young gamers alike.